Listed in: Biology, as BIOL-457
Caroline E. Goutte (Section 01)
This seminar will focus on understanding germ cells. Although germ cells do not contribute to the form or function of an individual, they have the important role of providing the continuity of life between generations. In many animals, they are among the first cells to be differentiated from others during embryonic development. Elaborate mechanisms ensure that the genetic information in these reproductive cells is protected and packaged in unique ways to be used in the next generation. We will explore primary literature readings that probe the specialized development and genetic regulation of germ cells in model systems such as mice, flies, and nematodes. Classic developmental genetic approaches as well as more modern molecular genetic methods will be discussed as ways of understanding these extraordinary cells. Students will use oral and written formats to present paper reviews and analyses. Three classroom hours a week.
Requisite: One of the following: BIOL 221, BIOL 241, BIOL 291, BIOL 370, BIOL 371 or consent of the instructor. Limited to 15 students. Spring semester. Professor Goutte.
If Overenrolled: priority will be given by seniority and by major (Biology, BCBP, Neuro)