Listed in: Biology, as BIOL-376
Joohyun Lee (Section 01)
Genes can undergo heritable modifications that alter gene expression without altering genetic information. Such modifications are known as epigenetic modifications, and are heritable through cell division (mitotic inheritance) or from parents to progeny (meiotic inheritance). Epigenetic modifications can be influenced by multiple biological and environmental factors, thus providing an added layer to the relationship between genotype and phenotype. Understanding how this layer of regulation works is becoming an important aspect of molecular genetics. In this course, we will cover basic concepts in epigenetics and discuss various epigenetic processes such as DNA methylation, chromatin remodeling, gene imprinting, post-translational histone modification, epigenomics, environmental epigenetics and the relationship between epigenetic modification and human health. Three hours of lecture per week plus one fourth hour per week.
Requisite: BIOL 191. Limited to 30 students. Spring semester. Visiting Assistant Professor Lee.
If Overenrolled: Priority will be given to Senior and Junior students